Methodology
The Syndrome Evaluation System
The Syndrome Evaluation System (SES) is a patented technology used for rapid multiplex amplification and accurate identification of virulence-associated genes of causative agents or organisms. This advanced platform surpasses conventional diagnostic tests by providing fast and precise results, especially when organisms are challenging to cultivate or locate. Currently, available diagnostic technologies for detecting infections are inadequate, often failing to detect early stages of illness and delaying specific therapy in critical cases, which can lead to functional loss or even loss of life.
The SES amplifies genes, enhancing the sensitivity of the test. The renaturation of the amplified signature gene to its chemically identified complementary gene sequence on the SES further improves accuracy.
Key Highlights of Minagene's CNS Infections Test:
Detects a greater number of cases compared to conventional methods
Reduction in Testing and Investigations
Avoids the need for multiple testing and unnecessary investigations, leading to cost savings
Reduces the duration of stay in the intensive care unit (ICU) and associated costs
Comprehensive Pathogen Detection
Detects DNA of various pathogens, including fungi, viruses, parasites, and bacteria, in a single test.
Capable of detecting both unimicrobial and polymicrobial infections.
Helps in confirming or excluding the presence of infections
Molecular Basis of Infectious Disease Diagnosis:
Molecular detection, which involves amplification and hybridization of nucleic acids, has revolutionized the diagnosis of infectious diseases. PCR (Polymerase Chain Reaction) is a commonly used method for nucleic acid detection in clinical laboratories. This approach allows for the direct detection of mutations associated with drug resistance in biological samples without the need for culturing the organism.
The molecular basis of diagnosis offers a new and innovative era in microbial diagnosis, improving the speed and accuracy of identifying infectious diseases. It enables targeted therapy and timely interventions, leading to better patient outcomes.
